CURRICULUM
VITAE
NAME: Edgar F.
Meyer, Jr.
April, 2008
TITLE: Professor
(Emeritus) of Biochemistry, Texas A&M University
Adjunct Professor, University of New Mexico, Taos
EDUCATION:
B.S. (Chemistry), North Texas State University, 1959
Ph.D. (Chemistry), University of Texas, 1963
EXPERIENCE
1996:
Visiting Professor, Dept. of Pharmacy, ETH,
Zürich, Switzerland
1993:
Deputy Chancellor's Research Award, Texas
A&M University
1992:
Visiting Professor, University of Florence,
Italy
1979-2003: Visiting Scientist,
Max-Planck Institute of Biochemistry,
Martinsried (Munich), Germany.
1967-2003: Assistant Professor,
Associate Professor, Professor, Dept. of
Biochemistry & Biophysics, Texas A&M University.
1976-1977: Sabbatical Leave,
Labor. für organische Chemie, Swiss Federal
Institute of
Technology (E.T.H.), Zürich, Switzerland.
1968-1977: Research Collaborator,
Brookhaven National Laboratory.
1966-1967: Post-doctoral Fellow,
Biology, Research with Professor
Levinthal,
Massachusetts Institute of Technology.
1965-1966: Post-doctoral Fellow,
Biology, Research with Professor
Alexander Rich,
Massachusetts Institute of Technology.
1963-1965: Post-doctoral Fellow,
Research with Prof.J.D. Dunitz, E.T.H.,
Zürich,
Switzerland.
SEMINAL ACCOMPLISHMENTS
- First use of color raster graphics for molecular modelling
(1968; Brookhaven National Lab.)
- Initialization of the Brookhaven Protein Data Bank (cf.
reference 88)
- First use of networking in the biological and life sciences
(cf.
reference 89)
RECENT PUBLICATIONS
82. "Structural Interaction of Natural and Synthetic Inhibitors with
the Venom Metalloproteinase, Atrolysin C (Ht-d)", D.Zhang, I.Botos,
F.X.Gomis-Rüth, R.Doll, C.Blood, F.G.Njoroge, J. Fox, W.Bode &
E.F.Meyer, Proc. Natl. Acad. Sci. USA(1994) 91:8447-8451.
83. "Crystal Structure of Atrolysin C and the Functional Properties of
the Non-proteinase (Pro-, Disintegrin-like, and High Cis) Domains in
Snake Venom Metalloproteinases", J.W. Fox, L.-G. Jin, T. Gyorfi, J.B.
Bjarnason, E. Meyer, J. Cell Biochem. (1994) 18D:133.
84. "The crystal structure of adamalysin II, a zinc-endopeptidase
from the snake venom of the Eastern diamondback rattlesnake, Crotalus
adamanteus" W. Bode, L.F. Kress, E.F. Meyer & F.X. Gomis Rüth
(1994) Brazilian J. Med. Res. 27:2049-2068.
85. "Structure-based Analysis of Inhibitor Binding to Ht-d", I. Botos,
L. Scapozza, J.D. Shannon, J.W. Fox & E. F. Meyer (1995), Acta
Cryst D.D51, 597-604.86. "Batimastat, A Potent Matrix
Metalloproteinase Inhibitor, Exhibits an Unexpected Mode of Binding",
I. Botos, L Scapozza, D. Zhang, L.A. Liotta & E.F. Meyer (1996),
Proc.Natl.Acad.Sci.USA, 93:2749-2754.
86. "Batimastat, A Potent Matrix Metalloproteinase Inhibitor,
Exhibits an Unexpected Mode of Binding", I. Botos, L Scapozza, D.
Zhang, L.A. Liotta & E.F. Meyer (1996), Proc.Natl.Acad.Sci.USA,
93:2749-2754.
87. "Structure of adamalysin II with peptidic inhibitors. Implications
for the design of tumor necrosis factor a convertase inhibitors"
F.-X.Gomis-Rüth, E.F. Meyer, L.F. Kress & V. Politi (1998),
Protein Science 7:283-292
88. “The First Years of the Protein Data Bank“, E.F. Meyer, (1997)
Protein Science 6:1591-1597
89. “A Brief History of Networking in the U.S.”, E.F. Meyer and N.F.
Funkhouser (1998), J.Chem.Infor.& Comp.Sci. 38:951-955.
90. “The crystal structure of recombinant mouse collagenase-3
(MMP-13)”, I. Botos, E. Meyer, S.M. Swanson, V. Lemaître, Y.
Eeckhout, and E.F. Meyer, (1999) J.Mol.Biol, 292: 837-844.
91. “The Structure of Fire Ant Chymotrypsin, C1”, Istvan Botos, Erik
Meyer, Myhanh Nguyen, Stanley M. Swanson, David Russell & E. F.
Meyer (2000); J.Mol.Biol, 298, (5). 895–901.
92. “Molecular Modelling & Drug Design” Edgar F. Meyer, Stanley M.
Swanson, & Jocylin A. Williams (2000), Pharmacology &
Therapeutics 85, 113-121
93. “WWWWhy Does Nature Stutter?”, E.F.Meyer & W.J.Tollett,
(2001), Acta Cryst D57,181-186.
94. "Construction, Expression, and Characterization of a
Baculovirally Expressed Catalytic Domain of Human Matrix
Metalloproteinase-9" (2001) S. Sadatmasnoori, J. MacDougall, S.
Khademi, L.S. Cooke, L. Guarino, E.F. Meyer & R. Forough. Protein
Expression and Purification 23 447-452.
95. “Determination of the structure of an endoglucanase
from Aspegillus niger and its model of inhibition by paladium chloride”
(2002) S. Khademi, D. Zhang, S. Swanson, A. Wartenberg, K. Witte &
E.F. Meyer, Acta Cryst., D58, 660-667.
96. “Structure of an endoglucanase from termite, Nasutitermes
takasagoensis” (2002) S. Khademi, L.A. Guarino, H. Watanabe, G. Tokuda
& E.F. Meyer, Acta Cryst., D58, 653-659.
97. “Digestive enzyme identified and effects offeeding serine
proteinase inhibitor to Solenopsis invicta (Hymenoptera:
Formicidae).(2002) Meyer, E. D., S. Ellison, S. B.Vinson and E.
Meyer Southwestern Entomologist Suppl. 25:81-88.
98. "Scaled Molecular Models and Sculptures" (2004) IEEE
Biomed/DART Symposium, London, UK. 1093-954/04, 229-234.
RECENT INVITED LECTURES
2001 “Extending our digital and visual perceptions“, at The Digital
Workbench: Computer Modeling, Data Processing, and Visualization in
Science and Technology, Max-Planck Institute for the History of
Science, Berlin
2005 “Get a Grip – Molecules You Can Handle”, Lemelson Foundation,
National
Museum of American History (Smithsonian), Washington D.C.
2005 Organized the MicroSymposium “Art in Crystallography”and art
exhibition at the 20th International Union of Crystallography,
Florence, Italy and presented the concluding lecture
2006 “Visualizing the Nano-World”
Calit2: University of
California - SanDiego
2008 "Antibiotics:
"‘Paradise lost,’ bit by bit, back to bacteria", Wheeler Peak Group,
Taos, NM
2008 - guest lectures, Taos High School
RECENT INVITED SEMINARS
2001 Max-Planck-Institute for the History of Science,
Berlin
Institut
für Kristallographie; Freie Universität Berlin
F.
Hoffmann-LaRoche, Basel, Switzerland
Novartis AG,
Basel, Switzerland
2002 Johnson & Johnson, San Diego, CA
Structural
Genomix, San Diego, CA
2004 IEEE 8th International Conference on Information
Visualisation (14-16 July 2004, London, UK)
http://molecular-sculpture.com