CURRICULUM VITAE

            
NAME:   Edgar F. Meyer, Jr.                                                               April, 2008

TITLE:    Professor (Emeritus) of Biochemistry, Texas A&M University
                  Adjunct Professor, University of New Mexico, Taos

EDUCATION:
                B.S. (Chemistry), North Texas State University, 1959
                Ph.D. (Chemistry), University of Texas, 1963

EXPERIENCE

    1996:             Visiting Professor, Dept. of Pharmacy, ETH, Zürich, Switzerland
    1993:             Deputy Chancellor's Research Award, Texas A&M University
    1992:             Visiting Professor, University of Florence, Italy
    1979-2003:    Visiting Scientist, Max-Planck Institute of Biochemistry,                   
                          Martinsried (Munich), Germany.
    1967-2003:    Assistant Professor, Associate Professor, Professor, Dept. of
                          Biochemistry & Biophysics, Texas A&M University.
    1976-1977:    Sabbatical Leave, Labor. für organische Chemie, Swiss Federal
                          Institute of Technology (E.T.H.), Zürich, Switzerland.
    1968-1977:    Research Collaborator, Brookhaven National Laboratory.
    1966-1967:    Post-doctoral Fellow, Biology, Research with Professor
                          Levinthal, Massachusetts Institute of Technology.
    1965-1966:    Post-doctoral Fellow, Biology, Research with Professor
                          Alexander Rich, Massachusetts Institute of Technology.
    1963-1965:    Post-doctoral Fellow, Research with Prof.J.D. Dunitz, E.T.H.,
                          Zürich, Switzerland.

    
SEMINAL ACCOMPLISHMENTS

-  First use of color raster graphics for molecular modelling (1968; Brookhaven National Lab.)
-  Initialization of the Brookhaven Protein Data Bank (cf. reference 88)
-  First use of networking in the biological and life sciences (cf. reference 89)

RECENT PUBLICATIONS

82. "Structural Interaction of Natural and Synthetic Inhibitors with the Venom Metalloproteinase, Atrolysin C (Ht-d)", D.Zhang, I.Botos, F.X.Gomis-Rüth, R.Doll, C.Blood, F.G.Njoroge, J. Fox, W.Bode & E.F.Meyer, Proc. Natl. Acad. Sci. USA(1994) 91:8447-8451.

83. "Crystal Structure of Atrolysin C and the Functional Properties of the Non-proteinase (Pro-, Disintegrin-like, and High Cis) Domains in Snake Venom Metalloproteinases", J.W. Fox, L.-G. Jin, T. Gyorfi, J.B. Bjarnason, E. Meyer, J. Cell Biochem. (1994) 18D:133.

84.  "The crystal structure of adamalysin II, a zinc-endopeptidase from the snake venom of the Eastern diamondback rattlesnake, Crotalus adamanteus" W. Bode, L.F. Kress, E.F. Meyer & F.X. Gomis Rüth (1994) Brazilian J. Med. Res. 27:2049-2068.

85. "Structure-based Analysis of Inhibitor Binding to Ht-d", I. Botos, L. Scapozza, J.D. Shannon, J.W. Fox & E. F. Meyer (1995), Acta Cryst D.D51, 597-604.86.  "Batimastat, A Potent Matrix Metalloproteinase Inhibitor, Exhibits an Unexpected Mode of Binding", I. Botos, L Scapozza, D. Zhang, L.A. Liotta & E.F. Meyer (1996), Proc.Natl.Acad.Sci.USA, 93:2749-2754.

86.  "Batimastat, A Potent Matrix Metalloproteinase Inhibitor, Exhibits an Unexpected Mode of Binding", I. Botos, L Scapozza, D. Zhang, L.A. Liotta & E.F. Meyer (1996), Proc.Natl.Acad.Sci.USA, 93:2749-2754.

87. "Structure of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor a convertase inhibitors"  F.-X.Gomis-Rüth, E.F. Meyer, L.F. Kress & V. Politi (1998), Protein Science 7:283-292

88. “The First Years of the Protein Data Bank“, E.F. Meyer, (1997) Protein Science 6:1591-1597

89. “A Brief History of Networking in the U.S.”, E.F. Meyer and N.F. Funkhouser (1998), J.Chem.Infor.& Comp.Sci. 38:951-955.

90. “The crystal structure of recombinant mouse collagenase-3 (MMP-13)”, I. Botos, E. Meyer, S.M. Swanson, V. Lemaître, Y. Eeckhout, and E.F. Meyer, (1999) J.Mol.Biol, 292: 837-844.

91. “The Structure of Fire Ant Chymotrypsin, C1”, Istvan Botos, Erik Meyer, Myhanh Nguyen, Stanley M. Swanson, David Russell & E. F. Meyer (2000); J.Mol.Biol, 298, (5). 895–901.

92. “Molecular Modelling & Drug Design” Edgar F. Meyer, Stanley M. Swanson, & Jocylin A. Williams (2000), Pharmacology & Therapeutics 85, 113-121

93.  “WWWWhy Does Nature Stutter?”, E.F.Meyer & W.J.Tollett, (2001), Acta Cryst D57,181-186.
 
94.  "Construction, Expression, and Characterization of a Baculovirally Expressed Catalytic Domain of Human Matrix Metalloproteinase-9" (2001) S. Sadatmasnoori, J. MacDougall, S. Khademi, L.S. Cooke, L. Guarino, E.F. Meyer & R. Forough. Protein Expression and Purification 23 447-452.

95.  “Determination of the  structure of an endoglucanase from Aspegillus niger and its model of inhibition by paladium chloride” (2002) S. Khademi, D. Zhang, S. Swanson, A. Wartenberg, K. Witte & E.F. Meyer, Acta Cryst., D58, 660-667.

96.  “Structure of an endoglucanase from termite, Nasutitermes takasagoensis” (2002) S. Khademi, L.A. Guarino, H. Watanabe, G. Tokuda & E.F. Meyer, Acta Cryst., D58, 653-659.

97.  “Digestive enzyme identified and effects offeeding serine proteinase inhibitor to Solenopsis invicta (Hymenoptera: Formicidae).(2002)  Meyer, E. D., S. Ellison, S. B.Vinson and E. Meyer Southwestern Entomologist Suppl. 25:81-88.

98.  "Scaled Molecular Models and Sculptures" (2004) IEEE Biomed/DART Symposium, London, UK. 1093-954/04, 229-234.

RECENT INVITED LECTURES

2001 “Extending our digital and visual perceptions“, at The Digital Workbench: Computer Modeling, Data Processing, and Visualization in Science and Technology, Max-Planck Institute for the History of Science, Berlin

2005 “Get a Grip – Molecules You Can Handle”, Lemelson Foundation, National Museum of American History (Smithsonian), Washington D.C.

2005 Organized the MicroSymposium “Art in Crystallography”and art exhibition at the 20th International Union of Crystallography, Florence, Italy and presented  the concluding lecture

2006  “Visualizing the Nano-World” Calit2: University of California - SanDiego

2008 "Antibiotics: "‘Paradise lost,’ bit by bit, back to bacteria", Wheeler Peak Group, Taos, NM

2008 - guest lectures, Taos High School


RECENT INVITED SEMINARS

2001    Max-Planck-Institute for the History of Science, Berlin
            Institut für Kristallographie; Freie Universität Berlin
            F. Hoffmann-LaRoche, Basel, Switzerland
            Novartis AG, Basel, Switzerland

2002    Johnson & Johnson, San Diego, CA
            Structural Genomix, San Diego, CA

2004   IEEE 8th International Conference on Information Visualisation  (14-16 July 2004, London, UK)


http://molecular-sculpture.com

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